Endesmal Bone, Mesenchyme Bone (Membrane Bone)

Endesmal bone, bone developed from mesenchyme (Membrane Bone) is bone that develops (from mesenchyme) in connective tissue by its direct ossification, without the initial formation of cartilage tissue. An example of such bones are the bones of the facial and brain sections of the skull.

Endesmal bone is formed from mesenchymal cells, which gather in dense clusters and then turn directly into bone tissue, bypassing the cartilage stage. This process is called intramembranous ossification. It is characteristic of the bones of the skull, lower jaw, clavicle and some other bones of the skeleton.

Unlike cartilaginous bone, endesmal bone does not have a growth zone. Its growth occurs due to the deposition of new layers of bone tissue under the periosteum. The precursor cells of osteoblasts here are osteogenic mesenchymal cells. Thus, endesmal bone is a type of bone formed directly from connective tissue.

Endesmal bone is bone that develops from mesenchyme, connective tissue that does not contain cartilage. It is an example of bones that develop without the formation of cartilage, such as the facial or brain bones of the skull.

Mesenchyme is a tissue that is formed from the mesoderm, the germinal layer, and is the basis for the development of many organs and tissues in the body. During development, mesenchyme can turn into bone if it is in the right place at the right time.

The process of bone formation from mesenchyme is called endesmal ossification. This process occurs in connective tissue and begins with the formation of cartilage on the surface of the mesenchyme. Cartilage then turns into bone tissue, and mesenchyme turns into bone matrix.

Bones developing from mesenchyme can be either long or short. They can be located in various parts of the body, including the skull, chest, pelvis and limbs. These bones have their own structure and function that is different from other types of bones.

Thus, bone, developed from mesenchyme (membranous bone), is an important element in the development of the human body. It creates strong and functional bones that provide support and protection for the body.

Endemic bone is a special type of bone that develops from mesenchymal tissue in connective tissue without the initial formation of cartilaginous tissue as in normal bone development. This type of bone is an important type of bone in the human body as it is involved in the formation of many organs and structures, including the skull.

The development of bone from mesenchyme is called mesenchymal osteogenesis (MS). As the name suggests, MS occurs in the mesenchyme, a tissue made up of progenitor cells.

Mezghima is a specialized connective tissue that is present in different parts of the body and specializes in the formation of various types of connective tissue or the organization of intercellular space, including bone. Bones arise through the activity of osteogenic cells, which form osteoblasts, secreting a matrix of collagen, proteoglycan, osteocalcin and other minerals. Bone developing directly from mesenchymal tissues is relatively rare; however, they are important for understanding bone development in general.

If bones developed only from the osteoblasts contained in the periosteum, then the bones would be fragile, thin, very short-lived, unable to withstand the high loads characteristic of bones under the strong periosteum. On the other hand, if all osteogenic cells had the ability to form directly from the bone matrix and connect it to each other, then shorter bones would arise, different from those we observe, and with a huge variety of proportions and properties in different animals. In addition, because of this, we must have bones throughout the entire surface of the body, virtually untouched by bone marrow, requiring huge reserves of energy from the central nervous system. To ensure the full development of long bones during embryonic life, a combination of two mechanisms is required: the first is the mechanisms of growth and restoration of normal growth in a situation where they are damaged, and the second is the formation of bone from a source other than the osteoblast present in the periosteum - marrow bone. so that the bone can withstand stress. In addition to this,

Endesis bone or bone developed from the mz. called a membrane; bones are typical examples of this species, such as the facial bones of the skull. The membrane does not have cartilage as the initial material for bone remodeling. Restructuring occurs in the connective tissue itself without previous cartilage, giving rise to bone tissue. After the restructuring of this tissue, the shape of the connective tissue apparatus is largely determined by the shape of the developing bone.