M-cholinoreception is the process of interaction of molecules of the neurotransmitter acetylcholine with receptors that are located on the postsynaptic membranes of neurons and effector cells. These receptors can be excited or inhibited depending on the concentration of acetylcholine in the synaptic cleft. One type of m-cholinergic receptor is the muscarinic receptor, which is excited by the action of muscarine. It is located in the postsynaptic membrane of effector organs and in the central nervous system, where it is involved in the regulation of various body functions such as respiration, heart rate, glandular secretion, etc.
The muscarinic receptor is a protein that consists of several subunits and has several functional groups. It binds to the acetylcholine molecule and activates a cascade of reactions that lead to changes in the electrical activity of neurons and effector cells. In this case, the muscarinic receptor can be blocked or stimulated by other molecules, such as antagonists or agonists.
Muscarinic receptor antagonists are substances that block the action of acetylcholine on the receptors, thereby preventing their activation. They are used in medicine to treat various diseases associated with disruption of the m-cholinergic system, such as glaucoma, intestinal atony and others.
Muscarinic receptor agonists are molecules that stimulate the action of m-cholinergic receptors, thereby causing their activation and changing the electrical activity of cells. They can be used as drugs to treat certain diseases, such as Parkinson's and Alzheimer's diseases, and to improve cognitive function in patients with dementia.
In general, m-cholinoreception plays an important role in the functioning of the nervous system and is the object of research in various fields of biology and medicine.