Methemoglobin

Methemoglobin or synonym: Gemiglobin Ferrigem are called carboxyheme hemoglobins, in which instead of iron hemoglobinogen there is methgal.

Methemoglobionem is an intermediate product of hemoglobin oxidation reactions in tissues; the oxygen released from it is about

Methemoglobin is a form of hemoglobin in which the divalent iron atoms are replaced by ferric iron. The formation of an iron complex with two oxygen-containing ligands is of decisive importance for the binding of oxygen in this way, but its structure also differs from that of the tetramer of normally oxidized heme in oxyhemoglobin. The hemication is a monomer and is in solution, which ensures complete solubility of the compound in comparison with pry-heme. The structure of meta-gem is such that

Title: "Methemoglobin"

Methemoglobin is one of the hemoproteins that give our bodies and birds their pink color. The protein hemin, which is part of its structure, is responsible for this.

**Differences in composition and structure**.

Formed by methemoglobin-like hemes from protoporphyrin IX. There are signal residues of neutral amino acids in the fourth position. The difference from hemoglobin is the presence of two sulfur atoms in steriltet. The shortened chains of the histidine fragment are glued together by a disulfide bridge. When carboxylation of histidine residues occurs, dimers appear—tetramers with an octameric center of molecular symmetry. Tetrameric molecules have the ability to reversibly interact with each other. The presence of methemoglobin tetramers in solutions explains the presence of electrochromism when measuring the absorption of hemoglobin solutions.