Microcyte

Blood cells that have a smaller body and nucleus compared to mature red blood cells are microcytes or micro-RBCs. If mature cells have a larger size (Rbc 7.3 - 8.5) than the nucleus, micro-erythrocytes have a smaller size than the nucleus (rbc = 6.7 - 7.4, nucleus = 4.3-5.0 ). The absence of processes and 2 nuclei in microcytes is caused by a delay in the differentiation of chromatin into the 3rd, 4th and 5th hypoploid rings.

Microcytes are a problem. At any given time, of the entire population, only less than half can be considered mature and adequate for the function performed. Typically this assessment is carried out in an automated hematology analyzer as part of the quality control process. Since interference from macroerythrocytes or large macrocytes (their size is close to the size of microerythrocytes) is possible in the environment of the automatic analyzer, under certain conditions these objects can be mistaken for microerythrocytes and then there will be