Neutropenia is one of the most common hematopoietic disorders, which is characterized by a decrease in the number of neutrophil granulocytes in the blood. Neutrophil granulocytes, also known as neutrophils, are a type of white blood cell responsible for protecting the body from infections and bacterial diseases.
Neutropenia can be caused by a variety of causes, including hereditary factors, acquired diseases, and cancer treatment. Some forms of neutropenia may be associated with autoimmune diseases such as leukocyte adrenergic deficiency (LAD) syndrome or agranulocytosis, which leads to bone marrow suppression and decreased neutrophil production.
Neutropenia can present with a variety of symptoms, including increased susceptibility to infections, increased fatigue, weakness, and weight loss. In cases of severe neutropenia, there is a possible risk of developing sepsis, which is a serious complication and requires immediate medical attention.
Diagnosis of neutropenia includes a peripheral blood test to determine the number of neutrophils, as well as additional tests to identify the causes of the disorder. Treatment depends on the underlying cause of the neutropenia and may include bone marrow stimulating drugs, anti-inflammatory drugs, antibiotics, and other treatments.
Despite the fact that neutropenia is a serious disease, modern diagnostic and treatment methods can effectively combat this hematopoietic disorder and prevent the development of complications. It is important to seek medical help for any changes in your health so that the disease can be identified and treated promptly.
Neutropenia: causes, symptoms and treatment
Neutropenia is a condition in which the level of neutrophil granulocytes in the blood decreases below normal. Neutrophils are important white blood cells that play a key role in fighting infections. Neutropenia can occur as an independent disease or be a symptom of other pathologies.
Causes of neutropenia
The most common causes of neutropenia include:
- Viral infections such as HIV, hepatitis, rubella, etc.
- Bacterial infections, including sepsis and tuberculosis
- Fungal infections
- Oncological diseases
- Chemotherapy and radiation therapy
- Autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus
- Inherited diseases such as Kostman's syndrome and Kostman's agranulocytosis
Symptoms of neutropenia
Neutropenia can manifest in a variety of ways depending on its cause and severity. However, the most common symptoms are:
- Frequent infections such as runny nose, flu, bronchitis, pneumonia, etc.
- Tumors and ulcers in the mouth
- Swelling and pain in the abdomen
- Frequent attacks of fever
- Fatigue and weakness
Treatment of neutropenia
Treatment for neutropenia depends on its cause and severity. In some cases, no treatment is required and neutrophil levels may recover on their own. However, more severe cases may require treatment including:
- Use of antibiotics and antifungals
- Immunoglobulin therapy
- Transfusion of blood or its components
- Surgical intervention
In conclusion, neutropenia is a serious condition that can lead to various complications, especially in immunocompromised patients. If you notice symptoms of neutropenia, consult your doctor for diagnosis and treatment. Seeking help early can help avoid serious complications.