Nikolsky Symptom

Nikolsky Symptom

Nikolsky's symptom or Nickelson's test is a simple diagnostic technique that is used by dermatologists to assess the condition of the stratum corneum and epidermis of a person. The symptom is determined by the presence of a symptom of fine folding of the skin against the background of a slightly stretched surface layer of the epidermis. This technique, relatively widespread among dermatologists, is commonly called Nikolsky’s symptom. This sign was discovered by University of Vienna professor Pyotr Damianovich Nikolsky, who was a famous dermatologist and scientist of his time. He used this method to clarify the diagnosis. Its essence lies in the possibility of detecting a symptom in a patient with various skin diseases (trophic ulcers, scabies, pityriasis versicolor). The reception is able to detect the presence of itching, inflammation, swelling, destruction (disorder) of the oral layer of the skin and the inner layers of the epidermis. Certain dermatological diseases are diagnosed if there is an expression in the fold that appears during the above test, as well as the presence of various types of rashes.

Nikolsky's symptom

**Nikolsky syndrome** or **benign migratory epidermal necrolysis is a** clinical syndrome characterized by a violation of the integrity of the skin, hair loss in certain areas of the head or the entire scalp, and peeling of the skin in this area. It manifests itself as “creeping” rashes of small bubbles, usually single or protruding from the general mass of the affected area. Typical localization affects the facial skin and scalp. The syndrome and its causes were described by the Russian doctor P.V. Nikolsky in 1889. It is a rare multifactorial disease. It is characterized by the spontaneous occurrence of the pathological process. In medical practice, the syndrome has a second name: a benign form of migratory focal epilepsy.

Etiology

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