Nonna Compression Syndrome

Nonne compression syndrome is a rare neurological disease characterized by unilateral abducens nerve palsy (n. abducens) in combination with a pseudotumor of the optic nerve.

This disease was first described in 1901 by the German neurologist Max Nonne (1861-1959). He found patients with unilateral paralysis of the extraocular muscles combined with papilledema (papilledema) on the same side.

The cause of this syndrome is not completely clear. It is assumed that there is an inflammatory process at the base of the skull, which leads to compression of the abducens nerve at its exit from the brain. It is also possible that the optic nerve is irritated by an inflammatory process, which is manifested by swelling of the optic disc.

For diagnosis, an MRI of the brain is performed, and the cerebrospinal fluid is also examined. Treatment includes the use of steroids and other anti-inflammatory drugs.

The prognosis for nonna compression syndrome may vary depending on the severity of the optic nerve damage. Often after treatment, the patient's condition improves.