Pages Cells

Paget cells are a histological cell type that is found in the upper layers of the skin. These cells are often observed in various forms of skin cancer, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Pagets are highly malignant cells with a high metabolic rate, which allows them to quickly grow and spread throughout the skin. Pagets are usually found in closed areas of the skin, such as folds or areas of high pressure, where the skin has poor blood supply, making it difficult to detect and treat early stage cancer.

Pagets may also be present in other cancers such as non-Hodgkin's lymphoma, cutaneous melanoma, and Kaposi's sarcoma.

One of the main symptoms of Paget's is the formation of spherical or dome-shaped formations that rise above the skin. Small openings called ducts may be visible in the center of these formations. This may indicate the presence of metastatic cells in the patient's internal organs, as well as the possibility of deeper lesions developing.

The appearance of pagets can vary from slightly raised to pronounced unevenness of the skin. Paget lesions may be brown, black, or pink, depending on the stage of the disease. A change in skin pigmentation around the tumor, the appearance of erythema or telangiectasia may also be observed.

When examining Paget, a characteristic feature is clearly visible - the location of the ducts located outside the cell. Inside the cell are mucus-like