Peptidyl dipeptidase

Peptidyl dipyptidases are proteolytic enzymes that are involved in the cleavage of peptide bonds between amino acids in proteins. These enzymes are part of the kininase family and have an important function in regulating many biological processes such as cell development, immune response, and blood pressure regulation.

There are several types of peptidyldipetidase, but the most studied is peptidyldipetidase-2 (PDP-2), also known as kininase I. PDP-2 belongs to the family of kininases, that is, enzymes that act on the region of the bond between two amino acids, allowing one amino acid to break peptide bond. The key role of this group of enzymes is that they are targets for drugs used to treat hypertension and a number of other diseases.