Periarteritis Nodosa

Periarteritis nodosa (periarteritis nodosa) is a systemic disease that affects the arteries and veins. It can lead to serious complications such as myocardial infarction, stroke and kidney failure. Periarteritis nodosa most often occurs in men over 50 years of age.

The main symptoms of periarteritis nodosa are muscle and joint pain, fever, weakness and fatigue. In some cases, ulcers on the skin may occur, which may lead to bleeding.

Treatment for periarteritis nodosa includes medications such as steroids, immunosuppressants, and anticoagulants. Surgery may also be required to remove blood clots or plaque that is blocking the arteries.

It is important to note that periarteritis nodosa is a fairly rare disease, so most cases are diagnosed late, when serious complications have already arisen. Therefore, it is important to undergo regular medical examinations for early detection and treatment of this disease.

**Periarterial (periartesial) nodular fibrosis** is a benign (rarely malignant) proliferation of perivascular connective tissue elements and most often affects the walls of arteries and lymphatic vessels, less often - cutaneous veins and venous sinuses.

**Patients with this pathology are characterized by:**

* Examination of the vascular system using radiopaque methods; * Skin biopsy of suspicious areas (if any); * Ultrasound of soft tissues;

Morphological changes are characterized by the appearance of many thin-walled, monomorphic, movably palpable formations located in the subcutaneous tissue, which can subsequently merge with each other. The most favorable prognosis is for the initial forms of the disease, since the rate of increase in nodular formations significantly depends on the degree of involvement of the vascular walls in the process, as well as on the nature of the atherosclerotic process. At the same time, the rapid increase in nodules of vascular origin is combined with the greatest likelihood of developing necrosis or gangrenous changes in the skin and underlying soft tissues.

The initial sign of the disease may be changes in skin color - the appearance of “purple spots” on the limbs, neck, and torso. Later, areas of thickened skin with typical purple or brown nodules appear in these places.