Pleurisia is inflammation of the pleura, which can be caused by various reasons. One of the forms of pleurisy is dry pleurisy.
Dry pleurisy is characterized by the absence of fluid in the pleural cavity. This means that the lungs cannot function properly because they cannot receive enough oxygen and nutrients.
One of the main symptoms of dry pleurisy is chest pain. The pain may be sharp or dull, and may be made worse by taking a deep breath or coughing. There may also be other symptoms such as cough, shortness of breath, fever, loss of appetite and general malaise.
Treatment for dry pleurisy may include antibiotics, anti-inflammatory drugs, and other medications. In some cases, surgery may be required.
It is important to remember that dry pleurisy can be life-threatening if not treated promptly. Therefore, if symptoms of dry pleurisy appear, you should consult a doctor for diagnosis and treatment.
Pleurisy in medicine is a non-inflammatory lesion of the pleura, characterized by the accumulation of inflammatory effusion fluid in the pleural cavity. However, the accumulation of exudate is not the main distinguishing sign of pleurisy. The disease is not accompanied by a significant rise in temperature, changes in the blood and the absence of typical changes in lung function.
- Etiology and pathogenesis
The etiology of the disease is unknown. A connection between the development of pleurosis and concomitant immunodeficiency, bronchopulmonary pathology and diseases of the cardiovascular system is assumed. The development of pleusis is possible when severe injuries or postoperative complications occur, and then in most cases the cause is hemo-pneumothorax. The process of inflammation of the pleura occurs in several stages:
1. Dystrophic and atrophic changes in the cells of the pleural membranes. They are usually associated with tissue hypoxia or concomitant diseases. This manifests itself, for example, with extensive lung tumors and total damage to the lung area (pneumonia, congestive pneumonia). Some morphologists distinguish the stage of changes in the vascular wall and disruption of the cellular structure of fibroblasts. 2. Phase of exudative inflammation. It is characterized by a massive release of formed elements of the leukocyte series from the vessels and the deposition of fibrin on the surface of the pleura. Thickening of the pleural layer occurs. Against the background of the cellular elements of the fibrous membrane, foci of sclerosis are noted - mucoid and chronically proliferative. At the final stage of the process, the serous-fibrous membrane thickens to the point of adhesion, but already in the initial stages degenerative changes in the pleural folds, thickening and compaction of the interlobular bridges are noted. In some cases, diffuse pneumopleurisy occurs, accompanied by the formation of a massive membrane. Along with the listed morphological changes, there is an increased content of immunoglobulins in scrapings of pleural fluid, serum protease, eosinophils and other markers of allergic inflammation. This stage of dry pleurisy occurs regressively, decreasing over several days. However, residual effects in the form of connective tissue scarring in any form of the disease do not respond well to conservative therapy.
3. Fibrous-coagulative or sclerotic stage. It causes a complete blockade of lung movements, leading to infarction and degeneration of the parenchyma, and the development of secondary alveolar hypoventilation. The pathology is accompanied by a shift of the mediastinum towards the diaphragm, decreased breathing and ventilation, and the formation of pleuropulmonary insufficiency. A large number of complications result from unsatisfactory hemostasis or profuse hemorrhage into the pleural cavity from a disintegrating vessel. An organ can become an anatomical substrate for infection if the integrity of the vascular walls is disrupted due to injury.
Dry pleurisy
Dry pleurisy is an inflammation in the membrane that covers the lungs and lines the inside of the chest cavity, without the accumulation of exudate (discharged fluid). Pleurisy is a condition characterized by inflammation of the lining of the lungs. Dry pleurisy is a lesion characterized by the absence of copious discharge in the pleural cavity. In this case, the inflammatory process affects the thin membranes between the lungs and pleural cavities. This inflammation is associated with lesions in