Syngamidosis is a rare and little-studied disease that affects the skin and subcutaneous tissues of humans. The name of the disease comes from the words “singamosis” (lat. from Greek snake venom and “dys” (γυμνος) - naked, empty. Syngamidosis most often affects women aged 25-45 years. According to statistics, up to 90% of patients have a history of skin diseases. Syngamy skin may appear swollen or blotchy, and yellowish fluid may be visible under the skin. Treatment of this disease is very difficult and often requires surgery. The disease develops due to microbial skin lesions caused by actinomycetes - Streptomyces pe