The Proliferative Phase

The proliferative phase is a stage of cyclic changes in the endometrium, which is characterized by the proliferation of all layers of this organ. In this phase, the endometrium becomes looser and thickens, which facilitates the implantation of a fertilized egg.

During the proliferative phase, estrogenic hormones influence endometrial cells, stimulating their growth and reproduction. This leads to an increase in the number of cells in the endometrium and an increase in its volume. In addition, in this phase, the synthesis of proteins and other substances that are necessary for the development of the embryo occurs.

The proliferative phase begins in the middle of the menstrual cycle and continues until ovulation. It ends when the egg leaves the ovary and is fertilized by a sperm. If fertilization does not occur, then the next phase begins - the secretory phase.

In general, the proliferative phase plays an important role in the process of fertilization and embryo development, so it must be maintained in a healthy state.

The proliferative phase is a stage of cyclical changes in the endometrium, which is characterized by the proliferation of all layers of the uterus. This phase begins in the middle of the menstrual cycle and lasts approximately two weeks.

At the beginning of the proliferative phase, approximately on days 12-14 of the cycle, the level of estrogen in a woman’s body begins to increase. This causes the uterus to begin preparing for the implantation of a fertilized egg. During this period, the endometrium begins to grow to provide a place for the fertilized egg to attach and develop the embryo.

During the proliferative phase, the uterus becomes more sensitive to estrogen, and any small concentration of estrogen can cause endometrial growth. This can lead to endometrial hyperplasia, a condition in which the uterus begins to grow larger than usual. Endometrial hyperplasia can lead to bleeding, abdominal pain and other unpleasant symptoms.

To avoid endometrial hyperplasia, it is necessary to monitor the level of estrogen and progesterone in the body. This can be done by taking hormonal contraceptives, which regulate hormone levels in the body and prevent the growth of the endometrium. In addition, women can undergo an ultrasound of the uterus to ensure there is no hyperplasia.

Thus, the proliferative phase of the endometrium is an important stage of the cycle that should be well studied. By following your doctor's recommendations and taking hormonal medications, you can avoid unpleasant consequences and maintain the health of your uterus for many years.