Toxidermy Vaccine

Vaccine toxiderma (t. vaccinalis; synonym vaccine rash) is an allergic reaction to the vaccine, manifested by a skin rash.

Vaccines can cause different types of rash - measles, roseola, urticarial, papular, etc. The rash usually appears 2-3 days after vaccination.

Diagnosis is based on anamnesis (development of a rash after vaccination), clinical picture and epidemiological data (presence of cases of allergic reactions to this vaccine).

Treatment is symptomatic - antihistamines. The prognosis is favorable. Vaccination is subsequently carried out under the supervision of an allergist with the preliminary administration of antihistamines.



Toxiderma vaccionides is a complex of symptoms manifested in the form of various elements of a rash (vesicles, spots, papules, etc.) when using vaccines with live attenuated cultural or weakened inactivated preparations in individuals sensitized to proteins and other components of the vaccine.

With vaccine toxicerma, due to an allergic skin reaction, intense red-violet erythematous skin lesions with small swollen and inflamed blisters in limited areas of the skin may occur. The development of the lesion is preceded by the presence of a small pustular rash at the injection site (urticarial, vesicular, fine blistering). The predominance of rashes over pronounced edema is characteristic. The rash is accompanied by moderate hyperthermia. Often the disease is accompanied by the appearance of an inflammatory focus in the subcutaneous tissue or fascia. In the presence of reactive lymphadenitis, anal treatment is added