One of the early manifestations of any disease is the so-called symptom Complaints - it is also called premorbid syndrome When analyzing patient complaints, one must take into account that their formulation largely depends on the patient’s personality, level of education, thinking and speech. Nevertheless, among the identified symptoms, their sequence and “order of occurrence,” there are some that reflect the general, natural course of formation of the disease state. These findings are called prodromal signs. Manifestations of the disease in the prodrome are nonspecific, and their clinical picture is poor and scarce. This condition occurs immediately before the formation of the manifest picture and is something between the norm and the disease.