Liver Abscess

A liver abscess is a cavity filled with pus and surrounded by an inflammatory infiltrate, located in the liver tissue or in its capsule. Liver abscesses are one of the most dangerous complications of acute hepatitis. They occur as the acute disease progresses in 4–25% of cases. Acute abscess is not an independent disease, but a complication of acute viral hepatitis. For example, the cause of an abscess can be either organ destruction due to necrotizing hepatitis, or invasive cholangitis and cholangiocholecystitis [12].

An abscess is the result of sequestration of a focus of acute inflammation. As a rule, abscesses occur in the liver several weeks or months after the onset of an acute viral disease when visible inflammation disappears and an acute inflammatory reaction in the liver tissue persists. This leads to the fact that inflammatory cells continue to actively multiply, destroying healthy hepatocytes. The resulting foci of such interstitial destruction begin to sequester as a result of the destruction of interstitial tissue and inflammation in it. As a result, secondary pathological cavities are formed. In this case, purulent exudate is separated from tissue detritus; thus cavities are formed. They are what are called secondary.