Globular Cell Anemia

Globular cell anemia (GC) is a rare hereditary disease that is characterized by impaired maturation and metabolism of hemoglobin in red blood cells. It is characterized by the appearance of abnormally large and irregularly shaped red blood cells with a high hemoglobin content. Such red blood cells are called macroerythrocytes or microspheres. In addition, with the globular type of anemia, an increase in the size of the spleen is observed, which is associated with its active participation in hematopoiesis. As a result, breathing problems arise due to disruption of oxygen transport through tissues, as well as disturbances in brain activity, dizziness, headache, and decreased performance of the body. The globular type of anemia can manifest itself at any age, but is most often diagnosed in older children and people of working age. This disease occurs more often among men than among women. SHAC has many factors of occurrence, including: 1. The hereditary nature of the mutation. 2. Chemical factors (ionizing radiation, certain medications, alcohol or drug use, toxic substances such as arsenic or lead). 3. Biological factors (acquired diseases that can lead to impaired formation of red blood cells and decreased hemoglobin levels