Natural antibodies are antibodies that are produced in the body in response to an infection or other foreign agent. They are part of the innate immune system and help the body fight infections.
Natural antibodies are synthesized by B lymphocytes without prior immunization. They can recognize common molecular structures shared by many microorganisms. Natural antibodies include IgM, IgG and IgA.
The main functions of natural antibodies:
- Antigen binding and neutralization
- Activation of the complement system
- Opsonization of microorganisms for phagocytosis
- Involvement in allergic and inflammatory reactions
Thus, natural antibodies are an important part of innate immunity and protect the body in the early stages of infection before the development of a specific immune response.