Basedow's Disease

Graves' disease (lat. morbus Basedovius) is a group of non-inflammatory diseases, the main symptom of which is diffuse hyperthyroidism caused by autoimmune destruction of thyroid cells with the development of thyrotoxicosis. Graves' disease is also called Graves' disease and primary thyroid hyperplasia. The clinical manifestations of the disorder are varied: excess body weight, the appearance of bulging eyes, trembling in the body, sweating, nervousness, increased blood pressure and tachycardia are common signs of the disease. Graves' disease requires complex treatment. Usually it consists of reducing the level of thyroid hormones and normalizing their levels. Treatment is carried out with thyreostatic agents and the use of iodinated contrast agents. If complications develop, surgery may be required.

Graves' urticaria

This is a disease that develops as a consequence of an autoimmune reaction in the thyroid gland. This leads to its enlargement (goiter) and thyrotoxicosis (increased levels of thyroid hormones - teroxin and triiodothyronine), which are characterized by polyclonal hyperplasia of the thyroid follicles and an increase in the mass of this gland. Thus, the disease does not have a specific name. This definition consists of two main words: “goiter” (from the French gorge - “larynx”, English goiter - “goiter”) and “tetrad”: “thyroid” - thyroid gland, “o” - a prefix, often denoting increased function, and “atitrest” means “atherotoxicosis”, that is, the first mention of the word implies the previous presence of an increased content of thyroid hormones in the patient’s blood - one or more, most likely - theriotoxicosis; the latter is almost always considered a side effect of radioactive iodine treatment in people suffering from atopic dermatitis or psoriasis[1].

Goiter usually

BASEDOW'S DISEASE (Morbus Basedowi, K. A. von Basedow), chronic. hyperplasia of the thyroid gland, characterized by hyper- and hypersecretion of thyroid hormones, which determines the development of the clinical picture of damage to the nervous system, cardiovascular system and other organs. Laid the beginning of endocrinology. In 1840, the English physician G. T. Basedow (T. V. Basedow; 1779-1827) observed increased blood pressure, sweating, palpitations, attacks of general anxiety, tachycardia and tremors in several women aged 20–30 years. In patients, he discovered diffuse hyperplasia of the thyroid gland and in November 1835 outlined histological findings. picture of the disease (“functional units” by Bazedov), which he considered to be foci of damage to the internal cellular structure of the gland parenchyma. He later noted symptoms of head enlargement and fundus changes. The histology of the case he studied is similar to the picture of chronic toxic goiter. Years later, A. Tosi and almost 5 years later R. Levy confirmed the existence of an enlarged thymus in Basedow. In the following decade, M. Bleibert (1918) first repeated the Baze case