Carboxylation is a chemical reaction that occurs between carbon dioxide (CO2) and organic substances such as amino acids, carbohydrates, lipids and other molecules. This reaction produces a carboxyl group (-COOH), which is an important functional group in biochemistry and chemistry.
Carboxylation plays a key role in the body's metabolism. For example, it occurs during the synthesis of proteins, fats and carbohydrates. During this process, carbon dioxide combines with glucose or other carbohydrate molecules to form carboxyl groups, which are then used to form new compounds.
In addition, carboxylation is involved in the regulation of blood sugar levels. When blood sugar levels rise, glucose is converted to glucose-6-phosphate through glycolysis. Glucose 6-phosphate then undergoes carboxylation, resulting in the formation of fructose 6-biphosphate, which serves as an energy source for cells.
Laboratory carboxylation is used for the synthesis of various organic substances. For example, acyloins can be prepared by carboxylation of acyls such as acetic acid or propionic acid. This process is often used in the synthesis of drugs and other chemical compounds.
Carboxylation is the reaction of addition of carbon dioxide CO2 or CO2 (hydrogen bicarbonates) H2CO3 to molecules of organic substances to form the carboxyl group –COO-. This reaction is called the carboxylic acid reaction.
The carboxylation reaction occurs under the influence of temperatures greater than 20 degrees Celsius and