Hemolysin is a protein that is found in the blood of some animals and can cause the destruction of red blood cells in individuals of another species. It is produced by the immune system and is used to destroy foreign agents such as bacteria and viruses.
Hemolysins can be normal and pathological. Normal hemolysins do not cause destruction of red blood cells and do not pose a threat to the health of individuals. They can be found in non-immunized animals that do not have antibodies to specific antigens.
Pathological hemolysins, on the contrary, can cause destruction of red blood cells and lead to anemia. They are produced by the immune system in response to foreign agents such as bacteria, viruses and parasites. Abnormal hemolysins can cause serious diseases such as hemolysis, hemoglobinuria and hemolytic anemia.
To determine the presence of hemolysins in blood serum, it is necessary to conduct a protein analysis. If the test result shows the presence of normal hemolysins, this means that the animal does not have immunity to certain antigens and may be at risk of infection. If the test results show the presence of pathological hemolysins, this may indicate the presence of an infection or other diseases.
Hemolysin (from ancient Greek ἕμαι - blood + λύσις “dissolution”) are molecules that specifically destroy cell membranes, with which they bind after preliminary adsorption on the cell surface or particles. Normally, blood cells are protected from destruction by the body’s own hemolysin. When a pathogen enters red blood cells, other types of hemolysins are released along with toxins into the body, which target specific cells of the body, for example, eukaryotic (S. aureus), anaerobic bacteria (Actinomyces odontolyticus) and gram-positive group D streptococci. Hemolysis during infection with blood in vitro turns out to be largely due to the toxicity of microbial lipases and exotoxins, rather than the actual antigens of microorganisms.