Heterokaryon

A heterokaryon is a kind of “hybrid” of two nuclei, which is created due to the specific processing of organisms containing DNA. The structure formed in this case is called heterokaryons. Heterokaryons can form both between individual organisms and between an organism and the extracellular phase. In the second case, we are talking about the impact of genotoxic factors on nuclear material. In heterokaryosis, both different cells of the same organism and heterologous cells from different organisms can interact.

The phenomenon of heterokaryon occurs in nature during the transplantation of nuclei from lymphoid cells. It is this that underlies the reaction of transplantation tolerance - a condition in which the recipient normally tolerates tissues and organs of foreign origin. This system is the basis for the effective use of xenografts in humans. To form heterocarines, the recipient can be injected with donor leukocyte fractions, fibroblasts or animal bone marrow. Ability