Glomerulonephritis

Diffuse glomerulonephritis is an immunoinflammatory kidney disease, which is characterized by damage to the glomeruli of the kidneys and a violation of their filtration function.

Key facts about diffuse glomerulonephritis:

  1. The causes are most often streptococcal infection, less often other infections, autoimmune diseases, allergies.

  2. Clinical manifestations of acute glomerulonephritis: edema, arterial hypertension, hematuria, proteinuria, renal dysfunction.

  3. Chronic glomerulonephritis occurs in various forms - latent, hypertensive, nephrotic, mixed.

  4. The diagnosis is based on urine tests, Zimnitsky test, blood pressure, and biochemical blood test.

  5. Treatment: diet, antibiotics, corticosteroids, cytostatics, antihypertensive drugs, pathogenetic therapy.

  6. Prevention: timely treatment of infections, identification and treatment of latent forms.

  7. If left untreated, the process may become chronic and develop chronic renal failure.



Glomerulonephritis: Understanding, Symptoms and Treatment

Glomerulonephritis, also known as Bright's disease, is an inflammatory kidney disease that affects the glomeruli (glomeruli) responsible for filtering blood. This condition can result from immune reactions, infections, or other disorders, and it can have various causes and presentations.

In glomerulonephritis, immune complexes, antibodies and other substances accumulate in the glomeruli, causing inflammation and damage to the kidney tissue. This can lead to poor kidney function, retention of fluid and waste in the body, and development of other problems such as hypertension and edema.

Symptoms of glomerulonephritis can vary depending on its form and severity. Some common signs include:

  1. Urine containing blood (hematuria) or foaming due to increased protein content in the urine (proteinuria).
  2. Swelling, especially around the eyes, legs and wrists.
  3. Fatigue and weakness.
  4. High blood pressure.
  5. Signs of infections, such as fever, sore throat, or cough.

The diagnosis of glomerulonephritis is usually based on a urine test to determine the presence of protein and blood, as well as kidney function testing and immunological tests. In some cases, a kidney biopsy may be required to more accurately determine the cause of the disease.

Treatment of glomerulonephritis depends on its form and severity. In some cases, anti-inflammatory drugs or immunosuppressants may be prescribed to reduce inflammation and control the immune response. Control of blood pressure and edema are also important aspects of treatment.

In cases of severe forms of glomerulonephritis, hemodialysis or kidney transplantation may be required. Hemodialysis helps clear the blood of waste and excess fluid when kidney function is severely impaired. Kidney transplantation may be considered if the kidneys have completely lost their function.

It is important to note that glomerulonephritis is a serious disease and its treatment requires the supervision of a urologist or nephrologist. Regular medical examinations and following your doctor's recommendations can help control the progression of the disease and maintain long-term kidney health.

In conclusion, glomerulonephritis, or Bright's disease, is an inflammatory disease of the kidneys that can lead to deterioration of kidney function. Early detection, accurate diagnosis and timely treatment play a crucial role in managing this condition. If you suspect glomerulonephritis or are experiencing associated symptoms, it is important to see your doctor immediately for evaluation and advice.

This article is provided for informational purposes only and does not replace medical advice. Consult a qualified healthcare professional for diagnosis and treatment.



Glomerulonephritis (from Ancient Greek γλωμμα - “glomerulus” and νεφρός, Late Latin nephros, plural nephrœ) is a group of diseases characterized primarily by inflammatory lesions of the glomeruli of the kidneys. Other names for the disease are nephrotic syndrome [NS], viral hemorrhagic respiratory nephritis [VHRN], nephropathy of pregnancy, diffuse proliferative glomerulonephritis. In most people with glomerulonephritis, the kidneys cope with their work, but with a chronic course, irreversible changes occur. This course leads to the fact that the kidneys cease to cope with blood filtration. And then a serious imbalance of nitrogen balance and dehydration of the body develops.

Glomuronephritis is a serious disease that can lead to impaired kidney function and even kidney failure. Therefore, it is very important to consult a doctor in a timely manner and undergo the necessary examinations.