Granulomatous cholangitis

Granulomatous cholangitis is a rare infectious disease that can affect the gallbladder, bile ducts and other abdominal organs. This disease is the result of a prolonged and intense attack by microbial agents such as bacteria, viruses and fungi, which can damage the walls of the bile ducts. Cholangitis poses a threat to the patient's life, so identifying the disease at an early stage is of great importance for treatment.

Cholangitis can be caused by a variety of microorganisms, including bacteria, fungi, and viral infections. However, the most common pathogens are bacteria of the intestinal family. Bacteria enter the bile through the blood and gastric mucosa, causing inflammation and the formation of granulomas on the walls of the bile ducts. The bacteria produce toxins and waste products that produce substances that damage the walls of the bile ducts, causing scarring and tissue sclerosis, leading to blockage of the bile ducts. It is also possible for a tumor to develop due to granulum formation.

Risk factors for the development of granulomatous cholangitis include long-term cholelithiasis, chronic obstructive liver disease