Ascanazi cells

Askanasi cells are an immortalized human fetal kidney cell line obtained from the kidneys of an aborted fetus in 1964. They were isolated and cultured in the laboratory of Dr. Leonard Hayflick in Philadelphia. These cells are widely used in scientific research due to their ability to divide indefinitely in culture.

Askanasi cells have a normal karyotype and express many proteins characteristic of epithelial cells. They can differentiate into various cell types, including adipocytes, osteoblasts, chondrocytes and neurons. This plasticity makes them a useful tool for studying cell differentiation and the signaling pathways that control gene expression.

Askanasi cells are widely used in genetics, toxicology, pharmacology and virology research. They make it possible to simulate many processes under normal and pathological conditions outside the body. These cells played an important role in studying the mechanisms of carcinogenesis and the search for new antitumor drugs.