Lepromin (Leptvmin)

Lepromin (Leptvmin) is a tissue extract prepared from skin lesions of patients with lepromatous leprosy.

Lepromine is used to diagnose leprosy. It is a suspension of killed mycobacteria leprosy in mineral oil. When injected into the skin of a healthy person, lepromin does not cause a reaction. However, a patient with leprosy develops an inflammatory reaction at the site of lepromin injection - a lepromin test. This is due to the fact that such patients have increased sensitivity to the causative agent of the disease.

Thus, a positive lepromin test indicates the presence of leprosy. Determining sensitivity to lepromin allows you to classify forms of leprosy and monitor the effectiveness of treatment.

Every year the number of patients with lepromatous type of disease is growing, which is associated both with an increase in the number of diagnoses and with health problems in developing countries. Every third person is a carrier of streptonestheside antibodies, which indicates that the disease is long-standing. Leprosy is prevalent mainly in rural areas of tropical countries: Africa, Asia, Latin America. The disease mainly affects men of working age. Many regions are seeing an increase in cases among children and adolescents. As is known, the pathology begins with an infection called Mycobacterium leprae and progresses to generalized lymphadenopathy or dermal manifestation. At the first stage of the disease there are no symptoms: the only sign

Lepromin is a tissue cell extract prepared from skin eruptions of the lepromatous type of leprosy. This disease affects the skin and bone skeleton, leading to disruption of their functioning and changes in appearance. Laboratory tests include microscopic examination of skin cells and a biopsy of the affected tissue. Tissue extraction provides clean and homogeneous samples for further testing.

The lepromatous type of leprosy is quite rare, accounting for less than one percent of all cases.