Physiological lipemia (Latin lipemia - fat content of milk, from Greek λίπος - fat and Latin -haema - blood; synonyms placental insufficiency, fetal dystrophy, fetal malnutrition) is a dysmetabolic lipid syndrome that occurs in women over 35 years of age during pregnancy; characterized by a low degree of fatty acid utilization by the liver and reduced activity of conversion enzymes. L.f. clinically manifested by trophic disorders of the skin and subcutaneous tissue of the hands and legs, a slight tendency to bleeding, and various extragenital manifestations. L.f is based on lipid disorders with a predominance of triglycerides. At the same time, normal levels of total cholesterol due to low values of LDL-C and type IIa hyperlipoproteinemia, characterized by a deficiency of high-density transport proteins, in the absence of other disorders of lipid and lipoprotein metabolism. In patients with L.f, free fatty acids are slightly increased and the ratio of dehydrotestosteronan per hemoglobin is decreased at values that do not correspond to age and family history.