Mediator Chemical

Chemical mediator

A chemical transmitter is a substance that is released by the ending of an axon in the area of ​​a synapse and activates a postsynaptic neuron or muscle.

Neurotransmitters play an important role in the transmission of nerve impulses. When an electrical signal (action potential) reaches the end of the axon, it causes the release of transmitter into the synaptic cleft. The transmitter diffuses through the gap and binds to receptors on the membrane of the postsynaptic cell, which either excites or inhibits it.

There are many different mediators. For example, acetylcholine, norepinephrine, serotonin, GABA, etc. Each of them plays a specific role in regulating various functions of the nervous system and the body. Disturbances in the synthesis or transmission of certain mediators underlie many neurological and mental diseases.