Neurath-Cushing syndrome

Neurath-Cushing syndrome is an endocrine disease characterized by overproduction of adrenal hormones (glucocorticoids) due to pituitary adenoma.

The syndrome is named after the Austrian pediatrician Neurath and the American surgeon Cushing, who independently described the symptoms of this disease at the beginning of the 20th century.

Main clinical manifestations: facial obesity (“moon-shaped”), skin lumbosity, stretch marks, arterial hypertension, osteoporosis, hyperglycemia, immunodeficiency.

The diagnosis is made based on the clinical picture, elevated cortisol levels and MRI of the brain (detecting a pituitary adenoma).

Treatment is primarily surgical - removal of the adenoma. Radiation therapy and medication are also used to normalize cortisol levels.

Untimely treatment leads to severe complications and disability of patients. Therefore, early diagnosis of Cushing's syndrome is extremely important.

Neurath-Cushing syndrome (neuroendocrine dysfunction) is a rare disease that is characterized by disruption of the endocrine system, in particular the hypothalamic-pituitary-adrenal axis. This condition can be caused by a variety of reasons, including genetic mutations, infections, tumors, trauma, and other factors.

Neurath-Cushing syndrome was first described in 1955 by Austrian pediatrician Rudolf Neurath and American surgeon William Cushing. It is characterized by increased production of adrenal hormones, which leads to various symptoms such as fatigue, weight loss, high blood pressure, muscle weakness, etc.

Treatment for Neurath-Cushing syndrome involves prescribing hormonal medications, such as corticosteroids, which help lower the levels of hormones in the blood. Other treatments, such as surgical removal of the tumor or immunotherapy, may also be used.

It is important to note that Neurath-Cushing syndrome is a rare disease and occurs in less than 1% of the population. However, if you notice any of these symptoms, you should consult a doctor for diagnosis and treatment.