Plethora Hyperkinetica

Plethora hyperkinetica is an incurable hereditary blood disorder characterized by abnormalities of red and white blood cells. It is caused by a mutation in the gene responsible for producing hemoglobin, causing these cells to lose their ability to carry oxygen to the body's tissues. This disease is a form of thalassemia that affects people all over the world. People may be born with plethora hyperkinetica or develop it years later.

The symptoms of this disease can be divided into two categories: hematological and non-hematological. Hematologic symptoms include changes in the blood, such as an increased platelet count or decreased red blood cell count. Lack of treatment for hematocrit values ​​above 60% can lead to hemolytic crisis when