Polyarteritis nodosa (PAN), also known as polyarteriopathy, is a form of systemic arterial disease caused by inflammation of the artery walls. The disease affects arteries throughout the body, including the aorta (the large artery that carries blood to other organs). It belongs to the group of vasculitides, which are a group of diseases that affect the blood vessels.
Polyarteritis is considered a relatively rare disease, but it remains one of the most dangerous and severe. Symptoms may include pain, swelling and weakness in the limbs, as well as an increased risk of complications from various organ systems. Treatment usually involves medications designed to reduce inflammation, and in severe cases, surgery or organ transplantation may be required.
The causes of polyarteritis nodosa are not fully understood, but often the disease is associated with infection, an allergic reaction, or damage to the immune system. As a result, narrowing of the arterioles can occur, leading to their destruction and the formation of blood clots. Other diseases can also cause PAN. These include cancer, herpes, syphilis, serum syndrome, etc.
For this reason, determining an accurate diagnosis and treatment are critical tasks. This is because PAN can lead to severe complications and even death of the patient if treatment is not started promptly. Various methods are used to treat PAN, including medications, immunosuppressive therapy, and interventional procedures such as angioplasty or stenting. The success of treatment depends on correctly prescribed