Potassium Permanganate

Potassium permanganate has a local cauterizing, resorptive hematotoxic (methemoglobinemia) effect. If ingested, a sharp pain appears in the oral cavity, along the esophagus, in the abdomen, vomiting, and diarrhea. The mucous membrane of the mouth and pharynx is swollen, dark brown, purple.

Possible swelling of the larynx and mechanical asphyxia, burn shock, motor agitation, and convulsions. Severe pneumonia, hemorrhagic colitis, nephropathy, and parkinsonism are often observed. When the acidity of gastric juice decreases, methemoglobinemia with severe cyanosis and shortness of breath is possible.

The lethal dose is about 1 g.

Treatment:

1. See Strong acids.
2. For severe cyanosis (methemoglobinemia) - methylene blue intravenously (50 ml of 1% solution), ascorbic acid (30 ml of 5% solution) intravenously.
3. Cyanocobalamin up to 1000 mcg, pyridoxine (3 ml of 5% solution) intramuscularly.
4. Treatment of toxic nephropathy, hepatopathy.

Potassium permanganate: a powerful antiseptic

Potassium permanganate is an antiseptic that is widely used in medicine. It has oxidizing properties and is used for washing wounds, lubricating ulcerative and burn surfaces, rinsing the mouth and throat, as well as for douching and rinsing in gynecological and urological practice. Potassium permanganate is also used for poisoning with various substances, such as alkaloids, morphine, nicotine, hydrocyanic acid, quinine and phosphorus. It is effective when aniline gets on the skin and when the eyes are damaged by poisonous insects.

Potassium permanganate is produced in various dosage forms, including powder and substance. The active substance is Potassium permanganate.

The producing country of Potassium permanganate is Russia, as well as some pharmaceutical companies, such as Asfarma, Barnaul pharmaceutical factory, Virion, Vladivostok pharmaceutical factory, Vologda pharmaceutical factory, Voronezhpharmacia and Voronezhkhimpharm. The drug is also produced at the Borisov Medical Preparations Plant in Belarus.

Potassium permanganate is an extremely powerful oxidizing agent and is highly active. Therefore, its use should be done with caution. Contraindications to the use of Potassium permanganate include hypersensitivity to the drug.

According to the literature, the side effects of Potassium permanganate are unknown. There is also no data on interactions with other drugs.

Caution must be exercised when using Potassium Permanganate to avoid overdose. If the drug is ingested, symptoms such as sharp pain in the mouth, along the esophagus, in the abdomen, as well as vomiting and diarrhea are possible. The mucous membrane of the mouth and throat may become swollen and dark brown or purple in color. In some cases, swelling of the larynx may occur and mechanical asphyxia or burns may develop.

In general, Potassium permanganate is a powerful antiseptic that is widely used in medicine. However, its use must be carried out under supervision and compliance with all necessary precautions.