Pemphigus Eye

Pemphigus of the eye (p. ocularis; synonym: bullous mucosynechial atrophic dermatitis, Lort-Jacob atrophic mucosynechial bullous dermatitis, benign pemphigoid of the mucous membranes, cicatricial pemphigoid, conjunctival p.) is a chronic recurrent disease characterized by the appearance on the conjunctiva and mucous membranes of the oral cavity, nose, pharynx, larynx, esophagus, vagina, rectum, blisters and erosions that are difficult to treat and leave behind scarring changes.

The disease begins with the appearance of vesicles on the conjunctiva, which quickly burst, leaving small erosions. The process is often bilateral. Subsequently, damage occurs to the mucous membranes of the oral cavity, and less commonly to the nose, larynx, esophagus, vagina, and rectum. Relapses of the disease are typical. Cicatricial changes lead to wrinkling of the conjunctiva and oral mucosa with the formation of symblepharons, trichiasis, entropion, laryngeal stenosis, and esophagus.

Treatment involves the appointment of glucocorticosteroid hormones, cytostatics, antihistamines, and physiotherapy. The prognosis is serious due to the recurrent course and tendency to scar changes.



Pemphigus Eye is a sluggish dermatitis on the mucous membrane of the eyelids with the appearance of small blisters. Usually the bubbles are translucent and located on the surface of the eyelids. Some of them are difficult to open due to the presence of a red base, although when cracks form, the edges remain uneven. Over time, the contents of some blisters may bleed through the pores of the lower eyelid, causing a yellow or greenish tint to the skin under the eye. Despite the fact that the appearance of pemphigus of the eyes is practically asymptomatic, in the first two years after infection, vision can be seriously impaired. It is important to consult a doctor as soon as possible to receive timely treatment and advice on further rehabilitation.