Renal Diabetes Insipidus.

azma, and the concentration coefficient does not exceed 1.1. This makes it possible to establish the diagnosis of nephrogenic diabetes insipidus.

Differential diagnosis should be carried out with other forms of diabetes, as well as with diseases that can lead to polyuria, such as acute and chronic pyelonephritis, diabetes mellitus, diabetic nephropathy, drug-induced kidney damage, hypercalcium, cystinosis and others.

Treatment. Treatment of nephrogenic diabetes insipidus is aimed at correcting water-salt imbalances and compensating for dehydration, as well as increasing the sensitivity of the renal tubules to ADH. It is also important to prevent recurrent episodes of dehydration and electrolyte imbalance.

First of all, it is necessary to ensure sufficient fluid intake to compensate for losses. Various solutions are used for this, including solutions of electrolytes, glucose, and water. It is also important to monitor electrolyte parameters, including the concentration of sodium, potassium, chlorine and other electrolytes in the blood.

In some cases, the use of thiazide diuretics, which increase the sensitivity of the renal tubules to ADH, may be effective. Research is also being conducted on new drugs aimed at increasing the sensitivity of the renal tubules to ADH.

Forecast and prevention. The prognosis of the disease depends on the degree of disturbance of the water-salt balance and the timeliness of the start of treatment. Timely treatment allows you to compensate for dehydration and electrolyte imbalance, and prevent delayed physical and mental development in children.

Prevention of nephrogenic diabetes insipidus involves prompt identification and treatment of diseases that can lead to this condition, as well as monitoring electrolytes and fluid balance in children at risk of developing the disease.

In conclusion, nephrogenic diabetes insipidus is a hereditary disease that manifests itself as impaired renal function and water-salt balance. The clinical picture of the disease can be varied, including excessive diuresis, vomiting, tendency to constipation, fever and other symptoms. Treatment is aimed at correcting dehydration and electrolyte imbalance, as well as increasing the sensitivity of the renal tubules to ADH. Timely treatment can help achieve compensation for disorders and prevent negative health consequences. It is also important to take preventive measures to identify and treat diseases that may lead to this condition, and to monitor electrolyte and fluid balance in children at risk of developing the disease.