Inflammation Interstitial

**Interstitial inflammation** is a complex, polymorphic, progressive process of generalized chronic inflammation, characterized by proliferation and inflammation of somatic cells of the interstitial tissue.

What is the interstitium?

Interstitium or interstitial (lat. Interstitium - located between) is an avascular intercellular connective tissue space within which cells are located, connecting with surrounding tissues using bundles of collagen fibers, giving the connective tissue the structure of a pericytic compartment. At the same time, the functional specialization of the interstitium remains variable and depends both on its localization and on the development of the tissue itself, and therefore varies very widely. In the lungs, liver, kidneys, stomach (to a lesser extent in the cardiac muscle), where the cells are of mesodermal origin (marginal and glandular cells of the mucous membrane), the interstitium is “native”, intratissue, but in most others

Inflammatory lung diseases are very common among the population of Russia and other countries. One of the diseases of the respiratory system is interstitial pneumonitis (IOP), an inflammatory disease of the lung tissue, characterized by widespread damage to the parenchyma like alveolar damage with the formation of fibrous and fibrinous changes in the connective tissue around the bronchi and vessels with infiltration of lymphocytes.

Interstitial pneumositis (IP) is an inflammatory process of the lungs of a diffuse nature, as a result of which destructive changes affect the entire lung tissue. The pathological process is dominated by replacement-proliferative processes, which lead to the formation of fibrotic changes in the lungs and disruption of their functionality. The development of IP is associated with impaired microcirculation of blood and lymph in the tissues of the lungs. Based on the location of the lesion, bilateral diffuse pneumonitis is distinguished, as well as a unilateral process of inflammation with predominant damage to the upper or lower lobes of one side (or several sides) of the lungs. In addition, it is customary to differentiate the inflammatory pulmonary process into hilar and widespread diffuse based on the place cough and respiratory syndromes occupy in its pathogenesis. The diagnosis of “diffuse alveolar pneumonitis” is correct only in cases where the patient does not have a malignant neoplasm, requiring x-ray examination of the affected parts of the mediastinum and pulmonary fields, during which it is possible to detect a clear symmetry of the “honeycomb” symptom