Peptic Ulcer of the Stomach and Twelve Tiper of the Bowel

Peptic Ulcer of the Stomach and Duodenum

A chronic recurrent disease, the main symptom of which is the formation of a defect (ulcer) in the wall of the stomach or duodenum.

Etiology, pathogenesis:

It is generally accepted that peptic ulcer disease is a polyetiological disease. Heredity, Helicobacter pylori infection, eating disorders, smoking, alcohol abuse, stress, and taking certain medications (non-steroidal anti-inflammatory drugs) predispose to the development of the disease. The direct formation of an ulcer occurs as a result of an imbalance between aggressive and protective factors of the mucous membrane of the stomach and duodenum.

Symptoms, course:

The leading symptom is pain in the epigastric region associated with eating. Nausea, vomiting, and weight loss may occur. Diagnosis is based on endoscopy and tests. The course is chronic with periodic exacerbations.

Complications: bleeding, perforation, stenosis, malignancy of the ulcer.

Treatment: diet, anti-Helicobacter therapy, antisecretory drugs, antacids. Maintenance therapy. Surgical treatment for complications.

Prevention: compliance with the work and rest regime, balanced nutrition, giving up bad habits, sanatorium treatment. Dispensary observation.