Relief Advance ointment instructions for use reviews

Relief Advance: instructions for use and reviews

Latin name: Relief Advance

ATX code: C05AD03

Active ingredient: benzocaine

Manufacturer: FAMAR (Greece), ISTITUTO de ANGELI (Italy)

Update of description and photo: 10/22/2018

Prices in pharmacies: from 428 rubles.

Relief Advance is an antihemorrhoidal drug.

Release form and composition

Dosage forms of Relief Advance:

1. ointment for rectal and external use: a homogeneous mass without foreign inclusions, white with a yellow tint, with a specific weak odor (28.4 g each in a plastic tube, 1 tube in a cardboard box, complete with an applicator);
2. rectal suppositories: torpedo-shaped, white with a yellow tint or white (6 pieces in a blister, 2 blisters in a cardboard pack).

1 g of Relief Advance ointment contains:

1. active ingredients: benzocaine – 0.2 g, shark liver oil – 0.03 g;
2. auxiliary components: mineral oil, propylene glycol, petroleum jelly, propyl parahydroxybenzoate, methyl parahydroxybenzoate, sorbitan monostearate.

1 suppository Relief Advance contains:

1. active ingredients: benzocaine – 0.206 g, shark liver oil – 0.06 g;
2. auxiliary components: cocoa bean butter, corn starch, methyl parahydroxybenzoate, solid fat, propyl parahydroxybenzoate.

Pharmacological properties

Pharmacodynamics

Relief Advance is a drug for topical use in proctology. It has anti-inflammatory, wound-healing and anesthetic effects.

The mechanism of action is determined by the properties of the components of the composition:

1. shark liver oil: has anti-inflammatory, wound-healing, hemostatic and immunomodulatory activity;
2. benzocaine: has a local anesthetic effect without causing resorption;
3. cocoa butter: being the basis of suppositories, it causes an additional softening effect.

Indications for use

1. anal itching;
2. internal and external hemorrhoids;
3. erosion and fissures of the anus.

Relief Advance is also used:

1. for pain relief after surgical operations in proctology;
2. during diagnostic procedures.

Contraindications

1. granulocytopenia;
2. thromboembolism;
3. hypersensitivity to the components of the drug.

According to the instructions, Relief Advance should be used with extreme caution and only as prescribed by a doctor during pregnancy, breastfeeding and for the treatment of children under 12 years of age.

Instructions for use of Relief Advance: method and dosage

Rectal suppositories

Relief Advance suppositories are used by insertion into the anus.

They should be used in the morning, at night and after each bowel movement (bowel movement), having previously carried out hygiene procedures.

Recommended dosage for patients over 12 years of age: 1 pc. no more than 4 times a day. The duration of treatment is determined individually.

Ointment for rectal and external use

Relief Advance ointment is intended for external use by applying a thin layer to the affected anal area and direct introduction into the anus.

The procedure is carried out using the supplied applicator, attaching it to the tube. Before insertion into the anus, the applicator should be lubricated by squeezing out a small amount of ointment. After each use, the applicator must be removed, washed thoroughly and placed in a protective cap.

Recommended frequency of procedures: up to 4 times a day (morning, afternoon, evening and after each bowel movement).

Side effects

During the use of Relief Advance, the development of allergic reactions and local reactions in the form of hyperemia and itching is possible.

Overdose

Symptoms: drowsiness, agitation, anxiety, and with significant intoxication – convulsions. Very rarely, systemic absorption of benzocaine can cause respiratory failure and cyanosis (methemoglobinemia).

Treatment: symptomatic therapy; for methemoglobinemia, intravenous administration of a methylene blue solution is indicated.

special instructions

If the drug accidentally enters the digestive tract, the patient requires immediate qualified medical attention.

If there is no clinical effect (while painful symptoms persist, heavy bleeding from the rectum), after 7 days of regular use of the drug, the patient must receive additional consultation with a proctologist.

Against the background of significantly exceeding the recommended dosage and the daily frequency of procedures, the shark liver oil included in the drug can cause the patient to develop a tendency to increased blood clotting.

Use during pregnancy and lactation

The use of Relief Advance during pregnancy and breastfeeding is possible in special cases if the expected effect of therapy for the mother exceeds the potential threat to the fetus or child.

Use in childhood

Use in children under 12 years of age is indicated only as directed and under close medical supervision.

Drug interactions

When Relifa Advance is combined with other drugs, no clinically significant interaction has been established.

Analogs

Analogs of Relief Advance are Relief, Relief Ultra, Relief Deep, Dentol, Anestezol, Hemoproct, Proctazol, Proctosan, Hemorol.

Terms and conditions of storage

Keep away from children.

Store at temperatures up to 27 °C, protected from light and moisture.

Shelf life – 2 years.

Conditions for dispensing from pharmacies

Available without a prescription.

Reviews about Relief Advance

Reviews about Relief Advance are more often positive. Patients indicate a rapid analgesic effect, healing of cracks, stopping bleeding and relieving itching, and a softening effect. The advantages of the drug include the presence of natural components in the composition and the ability to use during pregnancy and breastfeeding.

In severe stages of hemorrhoids, the medicinal properties of the drug are less noticeable.

Price for Relief Advance in pharmacies

Price for Relief Advance:

1. for a package of suppositories containing 12 pcs. - approximately 480 rubles;
2. for a tube of ointment – ​​401–482 rubles.

Relief Advance: prices in online pharmacies

Relief Advance 206 mg rectal suppositories 12 pcs.

RELIEF ADVANCE 12 pcs. suppositories Institute de Angeli

Relief Advance 20% ointment for rectal and external use 28.4 g 1 pc.

Relief advance supp. rect. n12

RELIEF ADVANCE 28.4g ointment

Relief advance rectal suppositories N12

Relief Advance rectal ointment 28.4 g

Relief Advance sup. rect. No. 12

Relief Advance rectal ointment 28.4g

Education: First Moscow State Medical University named after I.M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

Research shows that women who drink several glasses of beer or wine per week have an increased risk of developing breast cancer.

Millions of bacteria are born, live and die in our intestines. They can only be seen under high magnification, but if they were put together, they would fit in a regular coffee cup.

An educated person is less susceptible to brain diseases. Intellectual activity promotes the formation of additional tissue that compensates for the disease.

A person taking antidepressants will, in most cases, become depressed again. If a person has coped with depression on his own, he has every chance to forget about this condition forever.

During operation, our brain expends an amount of energy equal to a 10-watt light bulb. So the image of a light bulb above your head at the moment an interesting thought arises is not so far from the truth.

Each person has not only unique fingerprints, but also tongue prints.

When lovers kiss, each of them loses 6.4 calories per minute, but at the same time they exchange almost 300 types of different bacteria.

Smiling just twice a day can lower your blood pressure and reduce the risk of heart attacks and strokes.

Our kidneys are capable of purifying three liters of blood in one minute.

The highest body temperature was recorded in Willie Jones (USA), who was admitted to the hospital with a temperature of 46.5°C.

There are very interesting medical syndromes, for example, compulsive swallowing of objects. One patient suffering from this mania had 2,500 foreign objects in her stomach.

Tooth decay is the most common infectious disease in the world, which even the flu cannot compete with.

It was previously believed that yawning enriches the body with oxygen. However, this opinion has been refuted. Scientists have proven that yawning cools the brain and improves its performance.

The human stomach copes well with foreign objects without medical intervention. It is known that gastric juice can even dissolve coins.

Most women are able to derive more pleasure from contemplating their beautiful body in the mirror than from sex. So, women, strive to be slim.

The first wave of flowering is coming to an end, but the blossoming trees will be replaced by cereal grasses from the beginning of June, which will disturb allergy sufferers.

Medicines in the Relief series are intended for a comprehensive therapeutic effect on the intestinal mucosa, being very effective in the fight against hemorrhoids.

The product treats colon fissures well and eliminates symptoms of other diseases that are not related to hemorrhoids, perfectly relieves pain, has hemostatic properties, and helps accelerate regeneration processes.

In this article we will look at why doctors prescribe Relief Advance, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Relief Advance candles can be read in the comments.

Composition and release form

The drug Relief Advance is available in the dosage form of an ointment for external use and suppositories (suppositories) for administration into the rectal cavity. The ointment has a homogeneous viscous consistency, white color, candles are torpedo-shaped, small in size and white in color.

1. One gram of Relief Advance ointment, which is used externally or rectally, contains 200 mg of the active compound, and in addition, such auxiliary components as: sorbitan monostearate, oil obtained from shark liver, petroleum jelly, methyl parahydroxybenzoate, mineral oils, propylene glycol and propyl parahydroxybenzoate.
2. One Relief Advance suppository (suppository), intended for rectal use, contains 206 mg of a medicinal compound such as benzocaine, as well as the following auxiliary compounds: propyl parahydroxybenzoate, shark oil, methyl parahydroxybenzoate, cocoa bean butter and corn starch.

Clinical and pharmacological group: a drug with anti-inflammatory and local anesthetic effects for local use in proctology.

Indications for use

The use of Relief suppositories is recommended in the following cases:

1. external and internal hemorrhoids;
2. erosions and fissures of the anus;
3. anal itching;
4. for the purpose of pain relief after proctological operations;
5. during diagnostic procedures.

pharmachologic effect

This drug contains six main components that either provide treatment or provide an auxiliary effect:

1. Shark liver oil. This component is rich in vitamins and beneficial microelements, which allows you to treat inflammatory processes and effectively relieve the uncomfortable feeling of itching and burning in the anal area. Ointment and suppositories also help relieve pain.
2. Phenylephrine - helps to constrict blood vessels and improve blood flow in the area to which the drug is applied. This component plays a particularly important role during pregnancy, as well as in the presence of constipation.
3. Cocoa and Vaseline are oils. They not only help ease the administration of suppositories, but also have an anti-inflammatory effect, helping to relieve symptoms such as inflammation and itching.
4. Benzocaine helps relieve pain symptoms due to its local anesthetic effect.
5. Zinc sulfate - thanks to this component, damage to the mucous membrane heals.
6. Hydrocortisone acetate helps relieve swelling and itching; indications are also based on its vasoconstrictor and anti-allergenic effects.

The drug affects the body through absorption and actively affects not only the affected areas, but also the body as a whole.

Instructions for use

According to the instructions for use, both main forms of Relief Advance should be used only after hygienic procedures. Otherwise, the effectiveness of the drug is significantly reduced, and in some cases the patient’s condition may worsen.

1. Suppositories are inserted into the rectum in the morning, at night and after each bowel movement. Adults and children over 12 years of age are recommended to administer 1 suppository up to 4 times a day.
2. For children under 12 years of age, the drug is prescribed under medical supervision.

To use the ointment, remove the protective cap from the applicator, attach the applicator to the tube and squeeze out a small amount of ointment to lubricate the applicator. The ointment is carefully administered using an applicator up to 4 times a day (morning, afternoon and evening and after each bowel movement).

Contraindications

Among the contraindications for use are the following:

1. presence of Itsenko-Cushing syndrome;
2. diabetes mellitus in acute forms;
3. tuberculosis;
4. pregnancy, lactation;
5. the presence of any kind of infection - bacterial, viral and fungal;
6. the presence of hypersensitivity to some components of the drug.

Side effects

Relief ointment and suppositories may have the following side effects:

1. local side effects manifest themselves in the form of hyperemia (redness) or itching;
2. systemic or general represent the development of allergic reactions with various clinical manifestations.

If side effects occur, you should stop using the drug and seek advice from a specialist.

Analogues of Relief Advance

Among the analogues of the drug, the following drugs can be distinguished: Dentol, Hemoproct, Anestezol, Proctazol, Hemorol, Proctosan, Relief, as well as Relief Ultra and Relief Deep. Often patients faced with such an unpleasant disease as hemorrhoids are interested in which drug will be more effective in the fight against it - Relief Ultra or Relief Advance.

The average price of RELIEF ADVANCE, suppositories in pharmacies (Moscow) is 440 rubles.

Conditions for dispensing from pharmacies

The drug is approved for use as a means of OTC.

The description is valid on 12.02.2015

1. Latin name: Relief Advance
2. ATX code: C05AD03
3. Active substance: Benzocaine
4. Manufacturer: Sagmel, Inc. (USA)

Compound

The composition of the drug varies depending on the form of release of the drug.

In one suppositories (suppository) Relief Advance, intended for rectal use, contains 206 mg of such a medicinal compound as benzocaine, as well as the following auxiliary compounds: propyl parahydroxybenzoate, shark oil, methyl parahydroxybenzoate, cocoa butter and corn starch.

Contains one gram Relief Advance ointments, which is used externally or rectally, contains 200 mg of the active compound, and in addition, such auxiliary components as: sorbitan monostearate, oil obtained from shark liver, petroleum jelly, methyl parahydroxybenzoate, mineral oils, propylene glycol and propyl parahydroxybenzoate.

Release form

There are two main forms of this drug - suppositories And ointment.

Relief Advance candles They have a torpedo-shaped shape and are also distinguished by their white or yellowish color. Rectal suppositories are packaged in specialized packaging (PVC film blisters). One cardboard box usually contains two blisters with candles of 6 pieces each.

Ointment Relief Advance packaged in a tube with a nominal volume of 28.4 g. One cardboard package contains one tube of cream, as well as an applicator for ease of use.

pharmachologic effect

The drug belongs to the group antihemorrhoidal drugs, which have a pronounced wound healing, anti-inflammatory, and besides, local anesthetic properties.

Pharmacodynamics and pharmacokinetics

Since the drug contains valuable shark oil, containing alkoxy-glycerol and a row fat-soluble vitamin compounds, the drug is highly effective in treating hemorrhoids and provides wound healing, hemostatic, immunomodulatory, and anti-inflammatory effect.

It is worth noting that the active compound benzocaine, part of Relief Advance, belongs to the group of local anesthetics and therefore does not affect the body resorptive effect. Included in the medicine cocoa bean butter has softening properties.

Indications for use

Relief Advance is indicated for use in therapeutic treatment hemorrhoids, as well as if patients have anal itching And cracks in the tissues of the anus. In addition, this drug is used as painkiller when conducting proctological operations or diagnostic manipulations.

Contraindications

It is not recommended to use this medicine if you have elevated sensitivity, and thromboembolism And granulocytopenia.

Side effects

If the drug is used incorrectly, symptoms such as Aallergic reactions, itching, and hyperemia.

Instructions for Relief Advance (Method and dosage)

Both main forms of the drug should be used only after hygienic procedures. Otherwise, the effectiveness of the drug is significantly reduced, and in some cases the patient’s condition may worsen.

Relief Advance candles According to the instructions, it should be used rectally (i.e. inserted into the anus) 1 piece maximum 4 times a day. To achieve the best therapeutic effect, suppositories are recommended to be used in the morning, before bedtime, and also after each act of defecation (emptying the intestines).

The above rules for using the medicine are suitable for both adult patients and children over 12 years of age. The drug should be used during therapeutic treatment of patients under 12 years of age only after consultation with a doctor.

Ointment Relief Advance According to the instructions, it can be used both externally and rectally. Before using the drug, you should attach the applicator to the tube with the cream and squeeze out a certain amount of the drug for lubrication. The ointment should be applied no more than 4 times a day, preferably in the morning, before bed and after each bowel movement.

It should be remembered that after each use of the cream, it is necessary to thoroughly rinse the applicator and place it in a protective cap specially provided for this purpose. Ointment, as well as suppositories, can be used in the treatment of children under 12 years of age only with the permission of a pediatrician.

Overdose

If drug dosage recommendations are not followed, patients may experience symptoms benzocaine systemic absorption, i.e. convulsions, drowsiness, increased excitability, and methemoglobinemia, which is characterized by the presence cyanosis and respiratory distress. In case of overdose shark oilincluded in the drug may cause increased blood clotting.

Interaction

There is currently no data on interactions with other drugs.

Terms of sale

The medicine is dispensed from the pharmacy without a prescription.

Storage conditions

Relief Advance must be stored away from children, at a temperature of no more than 27 C, and always in a dry place.

Best before date

special instructions

It is recommended to immediately stop treatment with the drug and seek advice from a proctologist if bleeding from the rectum or in cases where the symptoms of the disease do not go away for more than 7 days from the start of therapeutic treatment.

Analogs

Among the analogues of the drug, the following drugs can be distinguished: Dentol, Hemoproct, Anestezol, Proctazol, Hemorol, Proctosan, Relief, and Relief Ultra and Relief Deep. Often patients faced with such an unpleasant disease as haemorrhoids, I’m interested in which medicine will be more effective in combating it - Relief Ultra or Relief Advance.

Unfortunately, even proctologists will not be able to give a definite answer to this question, since in each specific case patients will receive an individual effect from the use of these two drugs for hemorrhoids.

Synonyms

For children

As a general rule, the drug is not recommended for use in the treatment of children under 12 years of age, however, in agreement with the doctor and in case of urgent medical need, the use of the drug is allowed, taking into account the characteristics of each individual patient.

Relief Advance during pregnancy and lactation

At pregnancy and during lactation The drug can be used only after consultation with the attending physician, when he has conducted a comprehensive examination of the woman’s health status and was able to reliably assess the degree of possible risk and expected benefit for her and the child.

Reviews about Relief Advance

In Internet sources you can find various reviews about Relief Advance ointment, some of which are both positive and negative. Some patients who have tried the drug on themselves are satisfied with the result, however, there are also those for whom this drug was not suitable. Absolutely the same can be said regarding reviews of Relief Advance candles.

Relief Advance price, where to buy

Candles from hemorrhoids, like Relief Advance ointment, belong to a group of popular and widespread drugs that can be easily purchased at most pharmacies.

average price candles Relief Advance (package, 12 rectal suppositories), as a rule, does not exceed 360 rubles.

In some pharmacies the price Relief Advance ointments reaches 450 rubles.