Alteration Theory of Excitation

Alteration theory of excitation is a hypothesis that was proposed by Hermann von Helmholtz in 1854 to explain the mechanism of excitation in the nervous system. According to this theory, excitation occurs as a result of a change in the electrical potential in nerve cells, which leads to a change in their state and the transmission of a signal from one cell to another.

Alteration theory has several advantages over other arousal theories. First, it explains how electrical potential changes in nerve cells when excited. Secondly, it allows us to explain how signal transmission occurs from one nerve cell to another through synapses. Third, it helps to understand how the nervous system responds to external stimuli and how it can adapt to new conditions.

However, alteration theory also has its drawbacks. For example, it cannot explain why excitation occurs only in certain places in the nervous system, and not everywhere. In addition, it does not take into account other factors, such as chemicals and mechanical stress, that can affect the nervous system.

Despite this, alteration theory remains important for understanding the functioning of the nervous system and continues to be used in modern science. It helps scientists better understand how the nervous system works and how it can be used to treat various diseases.