Choline-Acetyltransferase

Choline acetyl transferase (Choline - acetyl transferase, XMT or ChAT) is an enzyme from the group of aminotransferases that catalyzes the reversible acetylation of compounds containing a sulfur atom, nitrogen or sulfur in the alpha position, for example, ethanolamine, mannose, cerebroside cation, L-carnitine, catecholamines (dopamine and norepinephrine), some B vitamins and polyamines. The enzyme is also capable of transferring the remainder of the amino group molecule from the amino acid to the resulting complex organic phosphate-anionic acetyl group. CMT has been identified in the tissues of the central nervous system as an early marker that occurs during the development of a pathological process in the brain. Material from Wikipedia - the free encyclopedia.