Infiltrate Leukocyte

The growing number of leukocytes found in tissues in the form of a cellular infiltrate is characterized by an inflammatory process, most often found in traumatic injuries and malignant diseases. During the inflammatory process, leukocytes can not only penetrate tissues, but also move from peripheral vessels, especially capillaries and microvessels, into the interstitial space. Hematogenous synthesis of leukocytes also leads to the accumulation of leukocytes in the tissue space. Thus, the pathology of the tissue response to mechanical injuries, infections or tumors can lead to the release of leukocytes from the vascular bed into the tissues. The involvement of lymphatic vessels in this process promotes the release of leukocytes through them back into the bloodstream, which explains the presence of inflammatory infiltration in trauma or malignant tumors. During intercellular movement, leukocytes also move to the bloodstream or break down into intercellular fluid, glucose and other metabolites. Infiltration is formed as part of the immune system's response to pathogenic activity in the body.