Joza-Sterling Symptom

Joseph Sterling syndrome is a clinical and radiological syndrome caused by increased production of cerebrospinal fluid in the brain parenchyma and stretching of the third ventricle and 4th ventricle.

Manifests itself in impaired consciousness, convulsions and dystonia. May be an early sign of increased intracranial pressure. Normally, the synthesis of cerebrospinal fluid is carried out mainly by the choroid plexuses of the lateral ventricles, but in pathology it can also occur in the brain itself, especially in the periventricular zone. The production of excess cerebrospinal fluid occurs in response to the development of hydrocephalus, during the period of active brain growth, in the presence of volumetric processes in the brain and in the supratentorial regions of the brain. With the development of cerebrospinal fluid hyperproduction, general cerebrospinal fluid production also increases and secondary and primary dislocation symptoms begin to form, which usually indicate more significant damage to the brain and cerebral hemodynamics.