Macrophage Free

Macrophages are cells in our body that perform a protective function. When a foreign body or pathogens enter our body, macrophages immediately respond to this signal and destroy them. Macrophages can be found almost everywhere: in the lungs, liver, intestines, skin and other organs.

They do not like any irritants entering the body, so they try to neutralize their effects. The surface layers of the skin are most affected. These cells are able to regulate the number of other human cells. For example, if we get several small scratches on the skin from something sharp, without causing any infection, then the macrophages will calm down and continue their work. If damage occurs and an infection enters, an inflammatory reaction will begin, attracting a large number of white blood cells. And then the formation of a secondary protective shell begins. The immune system will localize the problem and the wound will heal.

Free macrophages are free-swimming macrophages containing many different pyrunoid species; they are numerous in peripheral blood cells in both mammals and birds. The presence of free macrophages is observed in toluidine blue-stained rabbit blood samples. In these cells one can clearly see an accumulation of toluidine granules and a nucleus, but the processes of chromadophilic structures are practically absent. The average size of free macrophages is 1.25–1.85 times the diameter of the nucleus. The shape of free macrophages depends on their size and is determined by the degree of saturation with pyrunavides.