Miaz Tkanevoy

**Tissue myiasis** (m. textilea) is a parasitic invasion of the mucous membrane of the eyelid, paranchemosis of the eyelid and/or conjunctiva, accompanied by eosinophilic follicular keratoconjunctivitis.

Etiology and pathogenesis of _Worms_ M. textileum is a human parasite, the only one known in the fauna that lives as a tissue infection only in the epithelium of the skin appendage. However, it has not yet been discovered that some of the helminths in the inguinal lymph nodes belonged to an infected patient. It is likely that the female always parasitizes the skin, laying eggs which must then be transferred by the young helminth to the skin appendage, first to the scalp, before the helminth reaches maturity. It is assumed that the developmental cycle of M. textileus follows the typical pattern of the life cycle of microscopic worms. The development of the helminth can take place throughout the year on infected skin. The incubation period ranges from several weeks to several years. Clinically, two types of tissue myascus are distinguished. * The focal or local form of tissue myiasis occurs when the parasite resides locally in the skin or in the eye and nasal sinuses. * The generalized form of tissue-type myiasis is characterized by the spread of parasites throughout the skin or contact disorders of the hair follicles. The skin may become inflamed, causing itchy papules, blisters and eczema-like rashes that appear on the face and scalp. The skin is thickened with the development of granulomatous inflammation, characterized by the appearance of annular granulomatous membranes and many blisters on the plaque, as well as perifollicular reactions and intense purulent discharge. In some cases, pigmented granulomas, pseudoinflammatory cells, and the presence of parasitoid bodies may be present. The ocular form is characterized by moderate epidermotropic hyperpigmentation caused by a complex of genetic abnormalities; the presence of limited focal cortical and lymphatic pigmented lesions of the eyelid-conjunctiva. Similar diseases may appear at the stage of full manifestation when examining the eyelids for other diseases. Generalized myiasis may be more severe and may occur throughout the entire lesion, including the facial tissue and head. Although it is common in children, it can affect adults in areas of greatest contact with skin and hair, especially in areas of eczematous disease; in some cases it can penetrate the orbital sacs in Head or Ipsiga syndrome. It is generally accepted that chronic granulomatous myiasis is a symptom of chronic co-infection with M. xiphiura and C. bovis. Common diagnostic methods include microscopy, PCR diagnostics, enzyme immunoassay and genotyping. This disease most often occurs in childhood and is characterized by swelling of the tissue around the eyes. The disease manifests itself in the form of small nodules, lesions in the area of ​​the conjunctiva and skin around the eyes. Patients develop superficial ulcers