Myeloid leukemia Chronic

Myeloid leukemia, also known as chronic myeloid leukemia (CML), is a form of blood cancer that affects the bone marrow. This disease can cause healthy blood cells to multiply rapidly and crowd out other cells. As a result, patients may experience increased fatigue, fever, and enlargement of the spleen and other lymph nodes.

CML is caused by a mutation in the BCR-ABL gene. This gene is responsible for the production of a protein that regulates the production of healthy blood cells. When this gene is mutated, it begins to produce an abnormal amount of protein, resulting in an overproduction of abnormal cells. The abnormal cells begin to crowd out healthy cells, causing the symptoms mentioned above.

Chronic myeloid leukemia (CML) is a malignant neoplasm of the red bone marrow. Tumor formation occurs when chromosomes are damaged. In most cases it occurs during life, but often remains asymptomatic and is diagnosed incidentally. This is a systemic oncopathology. It is characterized by intensive proliferation of myelocyte precursor cells, which leads to their displacement of normal elements and the development of myelodysplastic syndrome and blast crisis. There is a hereditary predisposition. In total, there are three blood groups capable of responding to various factors of the internal environment. When cells receive a mismatch and chaotic changes occur in them. Cells acquire the properties and functions of sinuses and practically stop dividing. Their set of chromosomes increases, there are too many of them in a certain area. The tumor can grow in all directions. When blood cells begin to form, the disease is difficult to diagnose. Symptoms are absent or insignificant. There is a suspicion only when diagnosing a laboratory study of the composition of peripheral blood. This may include age over 45 years and a history of type 2 diabetes. At the same time, there are minimal symptoms of the disease: mild fatigue, increased body temperature, anemia, and possible gastrointestinal disorders. But it is necessary to understand that all these symptoms are characteristic of a large number of other diseases, therefore, in order to make a final diagnosis, it is necessary to conduct radiography/fibrocytoscopy of the abdominal organs/small intestines/mediastinum. With such studies, atypical nodules can be detected. Like any cancer, chronic myeloid leukemia cannot be completely cured. Therapy is aimed at containing the progression of the disease and relieving symptoms. There are two types of treatment for this: medication and surgery. Often both approaches are prescribed in combination. Meh