Osteoblastoclastoma [Osteoblastoclastoma; Osteoblast + (Osteo) Clast + -Ohm; Syn.: Gigantoma, Brown Tumor, Giant Cell Bone Tumor, Myeloid Tumor, Myeloplax Tumor, Osteoclastoma]

Osteoblastoclastoma, also known as gigantoma, brown tumor, giant cell bone tumor, myeloid tumor, myeloplax tumor, or osteoclastoma, is a bone tumor containing large numbers of multinucleated giant cells of the osteoclast type.

Osteoblastoclastoma often occurs in people between 20 and 40 years of age and can develop in any bone, but it most often occurs in long bones such as the femur, tibia, and humerus.

The tumor may be symptomatic or asymptomatic. If the swelling is symptomatic, symptoms may include pain, swelling, and limited movement in the affected area. If the tumor is close to nerves, numbness and weakness may occur.

The diagnosis of osteoblastoclastoma can be made based on X-ray examination or MRI. A tumor biopsy may also be necessary to confirm the diagnosis.

Treatment for osteoblastoclastoma may include surgical removal of the tumor, radiation, or chemotherapy. In some cases, a combination of these treatments may be needed.

The prognosis for patients with osteoblastoclastoma is usually good, especially if the tumor is found and treated early. However, in rare cases, the tumor may return after treatment.

In conclusion, osteoblastoclastoma is a bone tumor that may present with or without symptoms. Diagnosis may require an X-ray, MRI, or tumor biopsy. Treatment may include surgical removal of the tumor, radiation, or chemotherapy, and the prognosis is usually good.



Osteoblastomas are malignant neoplasms of bone tissue. This tumor often affects the bones of the skull, pelvis and upper extremities. Patients are often diagnosed with myxoid osteoblastoma, which is the most common bone tumor in the world. The myxoid variant of the tumor has a characteristic appearance - its volumetric formation on the periphery has a gray-pink or variegated, “cotton-like” (pretty) appearance due to the abundance of confluent cystic foci containing a foul-smelling, colorless, turbid liquid.