Bouchara Disease

Bouchard's Disease > Bouchard's disease, or Chronic spherocytic hemolytic anemia, cholosis syndrome, cryoglobulinemia - chronic hereditary or acquired hemoglobinuria, characterized by a violation of the functional properties of the erythrocyte membrane → spherocytes, anemia and hemolysis, as well as the presence of various markers of the pathological process in the blood and urine. > The disease was described by the French microbiologist Jean Baptiste Bouchardi in 1867, so the outdated name “Holosis”, “Chronicle of Blood” is often found in medical reference books. The disease is based on a pathological process consisting of a change in the surface charge of red blood cells associated with a decrease in cholesterol content and an increase in the level of bile acids.