Immunity Non-sterile

Non-sterile immunity (also known as infectious immunity) is the body's ability to resist infections and viruses without completely destroying them, but by inducing tolerance. On the other hand, such immunity occurs in the presence of infection. This property of immunity is necessary for the development of infections in animals and humans. From the moment a virus or bacteria enters the body, the process of an immune reaction begins, called nonspecific and guaranteeing the destruction of foreign agents.

During the process of formation of non-sterile type immunity, immunity can induce tolerance to the causative agent of the disease. Tolerance is the body's inability to eradicate a given disease and eradicate it even after exposure to its toxins or microorganisms. Also, these diseases can occur in a relatively mild form, which allows the body to fight the infection without the risk of life-threatening complications of the disease. The immune response becomes very strong as tolerance to the pathogen is established. Thus, the immune response subsequently becomes part of the response of the non-sterile defense system.

The nonspecific immune system develops tolerance through several mechanisms that occur over a longer period of time. In the early stages of non-sterile immunity, the body stimulates the production of specific IgM antibodies, which in turn attaches to foreign agents. If a certain amount of this type of antibody appears in the body, then the process of getting rid of infection is disrupted. In turn, this leads to the emergence of non-sterile immunity.

To form tolerance, the body creates a specialized, non-specialized T-lymphocyte system. This system performs the main function in the fight against infection, namely, it attacks cells already infected with the pathogen. The more cells are exposed to attack by the immune system, the faster it moves from a non-sterile phase to a sterile one. Thus, the non-sterile phase of protection passes into the sterile phase, ensuring the body's irreversible response to further infections. In the process of formation and development of a non-sterile response, the body's defenses can be weakened as the disease spreads. In general, the formation of a non-stereotypical response is a necessary process of protecting the body from infections and a response to the existence of tolerance towards the pathogens of these diseases. It helps fight infectious diseases and allows the immune system