Isoantigen System Kidd

Isoantigens are unique molecules inside cells that help the body distinguish between its own and foreign cells. There are several groups of these proteins, including the Systemic Kidd isoantigen. One of the best known serum isolates, called Anti-K, corresponds to a patient's antigenic glycoprotein associated with his platelets and red blood cells. The anti-K fraction is most often found in the form of a complex with antigen A. This serves as the basis for direct tests for antibodies against antigen 3 or antigen 4 that have been detected in plasma. Although Antibody MGT1 was originally intended to demonstrate the presence of antibodies against antigens 1 or 2, its functionality is assumed to reflect the functionality of YL molecules when bound to antibodies. The MGT antibody test can be used as a general test for allergic reactions to proteins. The specificity of antibodies to the Kidd system can be used for cloning purposes,

Kidd system isoantigens are a subtype of leukocytes that play an important role in protecting the body from infectious diseases. Isoantigens of the Kidd system are group antigens of leukocytes of the ABO system. They perform an important physiological function and have a high level of specificity. The structure of the Kidd system isoantigens are small protein molecules located on the surface of leukocytes.

The Kidd system is one of the largest antigen systems, which includes more than 200 isoantigen systems. These antigens make it possible to distinguish white blood cells from different people and facilitate the identification of pathogens of infectious diseases from a blood sample. In addition, different people may have different numbers and types of isoantigens, which may also indicate the presence of some problems. Some people with elevated levels of Kidd system antigens may have an increased risk of contracting infectious diseases because their bodies are not able to fight viruses and bacteria as effectively.

However,

Isoantigens of the Kidd system (Louis-Bar syndrome) are a group of genetically inherited disorders that arise due to mutations in the KLK7 gene. These disorders lead to an increase in the number of blood cells in the body and the development of various diseases such as aplastic anemia, lymphoma and multiple myeloid leukemia.

Genetic factors play a key role in the development of Louis-Bar syndrome. This mutation in the KLK7 gene can lead to the formation of toxic metabolites that can cause aplastic anemia (decreased number of blood cells). Also, there is a problem with the function of immune cells, which causes increased susceptibility to infections and complications.

At birth, a baby may experience signs of Louis Bar syndrome, such as weak muscle tone, poor coordination of movements, delays in speech development, etc. Over time, children become

Kidd system isoantigens are a family of leukocyte antigens that play an important role in the human immune system. These antigens were first described in 1927 by the American scientist Louis Kidd, who also coined the term "Kidd systems" to describe this family of antigens. Since then, Kidd systems have become one of the most studied classes of leukocyte antigens and are actively used in various fields of medicine, including immunology, oncology and transplantology.

Kidd systems are surface antigens of leukocytes, that is, molecules located on the surface of blood cells. They are represented by three main isoforms - K, k and Jk. Isoforms K and k are responsible for the class