An allergic reaction (AR) is one of the typical pathological processes that develops when an allergen enters the body and is characterized by damage to human tissues or organs through the formation of an immune complex on their surface, due to which the body’s defense system reacts by producing inflammatory cells (eosinophils, lymphocytes and others ).
The effect of an allergic reaction was noticed in 1819 by the English physician Hewson Bolton. Initially, the doctor decided to assume that there was an “internal poison” in the body, which subsequently formed swelling and inflammation over a short period of time. Webb first described a similar process, calling it a serum reaction. Due to the fact that this course turned out to be fatal, the new theory was never proven. Later, Bohlinger and Einstein discovered a similar pattern in bee stings, which allowed scientists to formulate a theory about the cause of AR-dangerous reactions.