Pallidectomy

Pallidectomy is a neurosurgical operation that involves destroying or modifying the function of the globus pallidus (see Basal Ganglia). The globus pallidus is part of the basal ganglia, a group of subcortical nuclei located in the brain.

This operation is used to reduce the manifestations of parkinsonism and other diseases accompanied by noticeable involuntary human movements. In Parkinsonism, there is a death of neurons in the substantia nigra of the brain, which produce the neurotransmitter dopamine. This leads to disruption of the regulation of motor activity by the basal ganglia and the appearance of characteristic symptoms (tremor, muscle rigidity, etc.).

Pallidectomy allows you to partially restore damaged connections in the basal ganglia and reduce the manifestations of the disease. Surgery may be performed using stereotactic radiofrequency to destroy the globus pallidus tissue. Pallidectomy is usually used for severe forms of parkinsonism when drug treatment is not effective enough.

Pallidectomy is a neurosurgical operation that involves destroying or modifying the function of the globus pallidus (one of the basal ganglia of the brain). This operation is used to reduce the manifestations of parkinsonism and other diseases accompanied by severe involuntary movements.

Pallidectomy is aimed at eliminating excessive activity of the globus pallidus, which leads to suppression of motor functions. Surgical intervention allows you to restore the balance of neuronal activity in the basal ganglia and thus reduce the manifestations of hyperkinesis. This operation is one of the options for surgical treatment of extrapyramidal disorders.

Pallidectomy is an effective way to improve motor activity in severe diseases such as Parkinson's disease, myoclonus epilepsy and other severe diseases associated with paroxysmal movement. The pallidum is a small area in the brain called the globus pallidus, which plays a key role in the appearance of involuntary movements that lead to falls and trembling of the limbs, for example, in Parkinson's disease. Thus, pallidectomy is aimed at destroying the centers responsible for these involuntary movements.

How is pallidectomy performed? Surgery on the base of the brain occurs under general anesthesia. The doctor makes a small incision on the patient's head. The brain is then switched off non-medically to relieve the patient of pain. This is done to prevent blood from being diverted to the patient's head, which could cause that person to have a stroke. After the patient has been immobilized, through two small holes created by the surgeon, the doctor penetrates directly into the pallida and destroys it using electrical and/or chemical impulses. Before the operation begins, the patient sleeps on his back (so that doctors can move overhead without causing a reaction). Coming out of the depths of the head during an operation, the doctor may end up in the depths of the brain for various reasons and remain there for a long time, but it must be remembered that in some cases with deep incisions this is inevitable, even with the use of modern technology. Damage to the brain during this procedure causes damage to some areas of the brain, including the cerebral cortex, which will be repaired where possible by transplanting fresh tissue (tissue grafting is a good possible option at this time).

What is the treatment for pallidectamia and Parkinson's disease? Here are some benefits of the procedure: * Patients return to normal daily activities, performing simple activities without the use of motors (movement or breathing, such as walking, talking, eating) - Paralysis and stiffness of the limbs - Trembling in the legs - Abnormal involuntary movements, including head tremors and hands When the procedure is used: Treatment for Parkinson's syndrome or epilepsy with Parkin's pas caused by (micro-muscles), sciatic disease, glaucoma and other serious diseases associated with involuntary movement Contraindications for pallidiectomy Pallidectomy, as a method of treatment, in all known cases has several contraindications due to possible complications such as strokes, infections and brain damage due to manipulation. This surgery also requires time to heal, and patients may use rehabilitation treatments for up to 6 weeks after the procedure.